Giovanni Pico della Mirandola (ˈpiːkoʊ_ˌdɛlə_mɪˈrændələ,_-ˈrɑːn- , dʒoˈvanni ˈpiːko della miˈrandola; Johannes Picus de Mirandula; 24 February 1463 – 17 November 1494) was an Italian Renaissance nobleman and philosopher. He is famed for the events of 1486, when, at the age of 23, he proposed to defend 900 theses on religion, philosophy, natural philosophy, and magic against all comers, for which he wrote the Oration on the Dignity of Man, which has been called the "Manifesto of the Renaissance", and a key text of Renaissance humanism and of what has been called the "Hermetic Reformation". He was the founder of the tradition of Christian Kabbalah, a key tenet of early modern Western esotericism. The 900 Theses was the first printed book to be universally banned by the Church. Pico is sometimes seen as a proto-Protestant, because his 900 theses anticipated many Protestant views.
Giovanni was born at Mirandola, near Modena, the youngest son of Gianfrancesco I Pico, Lord of Mirandola and Count of Concordia, by his wife Giulia, daughter of Feltrino Boiardo, Count of Scandiano. The family had long dwelt in the Castle of Mirandola (Duchy of Modena), which had become independent in the fourteenth century and had received in 1414 from the Holy Roman Emperor Sigismund the fief of Concordia. Mirandola was a small autonomous county (later, a duchy) in Emilia, near Ferrara. The Pico della Mirandola were closely related to the Sforza, Gonzaga and Este dynasties, and Giovanni's siblings wed the descendants of the hereditary rulers of Corsica, Ferrara, Bologna, and Forlì.
Born twenty-three years into his parents' marriage, Giovanni had two much older brothers, both of whom outlived him: Count Galeotto I continued the dynasty, while Antonio became a general in the Imperial army. The Pico family would reign as dukes until Mirandola, an ally of Louis XIV of France, was conquered by his rival, Joseph I, Holy Roman Emperor, in 1708 and annexed to Modena by Duke Rinaldo d'Este, the exiled male line becoming extinct in 1747.