A lesbian is a homosexual woman or girl. The word is also used for women in relation to their sexual identity or sexual behavior, regardless of sexual orientation, or as an adjective to characterize or associate nouns with female homosexuality or same-sex attraction. The concept of "lesbian" to differentiate women with a shared sexual orientation evolved in the 20th century. Throughout history, women have not had the same freedom or independence as men to pursue homosexual relationships, but neither have they met the same harsh punishment as gay men in some societies. Instead, lesbian relationships have often been regarded as harmless, unless a participant attempts to assert privileges traditionally enjoyed by men. As a result, little in history was documented to give an accurate description of how female homosexuality was expressed. When early sexologists in the late 19th century began to categorize and describe homosexual behavior, hampered by a lack of knowledge about homosexuality or women's sexuality, they distinguished lesbians as women who did not adhere to female gender roles. They classified them as mentally ill—a designation which has been reversed since the late 20th century in the global scientific community.
Women in homosexual relationships in Europe and the United States responded to the discrimination and repression either by hiding their personal lives, or accepting the label of outcast and creating a subculture and identity. Following World War II, during a period of social repression when governments actively persecuted homosexuals, women developed networks to socialize with and educate each other. Gaining greater economic and social freedom allowed them to determine how they could form relationships and families. With second-wave feminism and the growth of scholarship in women's history and sexuality in the late 20th century, the definition of lesbian broadened, leading to debate about the term's use. While research by Lisa M.
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Homophobia encompasses a range of negative attitudes and feelings toward homosexuality or people who identify or are perceived as being lesbian, gay or bisexual. It has been defined as contempt, prejudice, aversion, hatred or antipathy, may be based on irrational fear and may sometimes be related to religious beliefs. Homophobia is observable in critical and hostile behavior such as discrimination and violence on the basis of sexual orientations that are non-heterosexual. Recognized types of homophobia include institutionalized homophobia, e.
is an initialism that stands for "lesbian, gay, bisexual, and transgender". In use since the 1990s, the initialism, as well as some of its common variants, functions as an umbrella term for marginalized sexualities and gender identities. The term LGBT is an adaptation of the initialism , which began to replace the term gay (or gay and lesbian), in reference to the broader LGBT community beginning in the mid-to-late 1980s. When not inclusive of transgender people, the shorter term LGB is still used instead of LGBT.
A transgender person (often abbreviated to trans person) is someone whose gender identity differs from that typically associated with the sex they were assigned at birth. Many experience gender dysphoria, which they may seek to alleviate through transitioning, often adopting a different name and set of pronouns in the process. They may pursue gender affirming care such as hormone replacement therapy and various gender-affirming surgeries. Not all transgender people desire these treatments and others may be unable to access them for financial, medical or legal reasons.
Background. In human immunodeficiency virus (HIV), the relative contribution of genetic background, clinical risk factors, and antiretrovirals to chronic kidney disease (CKD) is unknown. Methods. We applied a case-control design and performed genome-wide g ...