"The Chemical Basis of Morphogenesis" is an article that the English mathematician Alan Turing wrote in 1952. It describes how patterns in nature, such as stripes and spirals, can arise naturally from a homogeneous, uniform state. The theory, which can be called a reaction–diffusion theory of morphogenesis, has become a basic model in theoretical biology. Such patterns have come to be known as Turing patterns. For example, it has been postulated that the protein VEGFC can form Turing patterns to govern the formation of lymphatic vessels in the zebrafish embryo.
Reaction–diffusion system
Reaction–diffusion systems have attracted much interest as a prototype model for pattern formation. Patterns such as fronts, spirals, targets, hexagons, stripes and dissipative solitons are found in various types of reaction-diffusion systems in spite of large discrepancies e.g. in the local reaction terms. Such patterns have been dubbed "Turing patterns".
Reaction–diffusion processes form one class of explanation for the embryonic development of animal coats and skin pigmentation. Another reason for the interest in reaction-diffusion systems is that although they represent nonlinear partial differential equations, there are often possibilities for an analytical treatment.
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The objective of this course is to expose students to the fundamentals of mechanobiology. We will highlight the technologies that enable the study of living systems including mechanical manipulation a
L'énoncé théorique de master constitue la première partie du Projet de Master. L'étudiant·e pose les bases théoriques de son travail, décrit le cadre thématique, référentiel et méthodologique.
Il·elle
Students will learn essentials of cell and developmental biology with an engineering mind set, with an emphasis on animal model systems and quantitative approaches.
The Turing pattern is a concept introduced by English mathematician Alan Turing in a 1952 paper titled "The Chemical Basis of Morphogenesis" which describes how patterns in nature, such as stripes and spots, can arise naturally and autonomously from a homogeneous, uniform state. The pattern arises due to Turing instability which in turn arises due to the interplay between differential diffusion (i.e., different values of diffusion coefficients) of chemical species and chemical reaction.
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side.
Patterns in nature are visible regularities of form found in the natural world. These patterns recur in different contexts and can sometimes be modelled mathematically. Natural patterns include symmetries, trees, spirals, meanders, waves, foams, tessellations, cracks and stripes. Early Greek philosophers studied pattern, with Plato, Pythagoras and Empedocles attempting to explain order in nature. The modern understanding of visible patterns developed gradually over time.
In this thesis, the generation of microcombs under complex, non-trivial, and/or higher-order cavity conditions is explored, both in theory & simulation, and in practical experimentation. Pulse-driving of microresonators is investigated for the generation ...
The form and structure of biological tissues define their function. The emergence of tissue morphology during development is one of the wonders of nature. Cells mechanically probe and manipulate their surroundings while constructing structures from the ext ...
EPFL2021
Shaping embryonic tissues into their functional morphologies requires cells to control the physical state of the tissue in space and time. While regional variations in cellular forces or cell proliferation have been typically assumed to be the main physica ...