İskenderun (إسكندرونة), historically known as Alexandretta (Αλεξανδρέττα, little Alexandria) and Scanderoon, is a city in Hatay Province on the Mediterranean coast of Turkey. Located on an alluvial plain, the city was heavily damaged by powerful earthquakes in February 2023 and subsequent aftershocks, floods and fires.
The city's history dates back to 333 BC, when it was founded by Alexander the Great as Alexandretta. It subsequently fell under Seleucid rule before being conquered by the Romans. After defeating the Byzantines in the 8th century, the Abbasid Caliphate gained control of the city. During the First Crusade, it came under the control of the Principality of Antioch before being captured by the Mamluk Sultanate.
By the 15th century, the Ottomans had conquered the city, maintaining control over it until the partition of the Ottoman Empire after the Allied victory in World War I. It subsequently became a sanjak in the French mandate of Syria until 1938, when France granted the region independence. The city became part of the Hatay State which in turn united with Turkey in 1939.
The city was founded as Alexandria (Ἀλεξάνδρεια) to commemorate Alexander the Great's victory over the Persian Darius III at Issus (Cilicia) in (333 BC). Starting in the Middle Ages, Western pilgrims used the diminutive Romance form Alexandretta.
İskenderun preserves the name, but probably not the exact site, of Alexandria ad Issum. The settlement was so called having been founded by Alexander the Great in 333 BC to supersede Myriandus as the key to the Syrian Gates, about 37 km (23 miles) south of the scene of his victory at the Battle of Issus against the Persian King Darius III. Alexander camped in the highlands of İskenderun, around Esentepe, and then ordered the city to be established and named Alexandria. İskenderun is one of many cities founded on Alexander's orders, including Alexandria, Egypt. A memorial, a monument and a bronze statue for the victory raised at the city, and Herodian writes that they were there even at his time, 200 AD.