Directed panspermia is the deliberate transport of microorganisms into space to be used as introduced species on other astronomical objects. Historically, Shklovskii and Sagan (1966) and Crick and Orgel (1973) hypothesized that life on the Earth may have been seeded deliberately by other civilizations. Conversely, Mautner and Matloff (1979) and Mautner (1995, 1997) proposed that humanity should seed other planetary systems, protoplanetary discs or star-forming clouds with microorganisms, to secure and expand its organic gene/protein lifeform. To avoid interference with local life, the targets may be young planetary systems where local life is unlikely. Directed panspermia can be motivated by biotic ethics that value the basic patterns of organic gene/protein life with its unique complexity and unity, and its drive for self-propagation. Directed panspermia is becoming possible due to developments in solar sails, precise astrometry, the discovery of extrasolar planets, extremophiles and microbial genetic engineering. Cosmological projections suggest that life in space can then have a future. An early example of the idea of directed panspermia dates to the early science fiction work Last and First Men by Olaf Stapledon, first published in 1930. It details the manner in which the last humans, upon discovering that the Solar System will soon be destroyed, send microscopic "seeds of a new humanity" towards potentially habitable areas of the universe. In 1966, Shklovskii and Sagan speculated that life on Earth may have been seeded through directed panspermia by other civilisations, and, in 1973, Crick and Orgel also discussed the concept. Conversely, Mautner and Matloff proposed in 1979, and Mautner examined in detail in 1995 and 1997 the technology and motivation to secure and expand our organic gene/protein life-form by directed panspermia missions to other planetary systems, protoplanetary discs and star-forming clouds. Technological aspects include propulsion by solar sails, deceleration by radiation pressure or viscous drag at the target, and capture of the colonizing micro-organisms by planets.