Nicotine withdrawal

Nicotine withdrawal is a group of symptoms that occur in the first few weeks after stopping or decreasing use of nicotine. Symptoms include intense cravings for nicotine, anger or irritability, anxiety, depression, impatience, trouble sleeping, restlessness, hunger or weight gain, and difficulty concentrating. Withdrawal symptoms make it harder to quit nicotine products, and most methods for quitting smoking involve reducing nicotine withdrawal. Quit smoking programs can make it easier to quit. Nicotine withdrawal is recognized in both the American Psychiatric Association Diagnostic and Statistical Manual and the WHO International Classification of Diseases. The most documented symptoms of nicotine withdrawal are cravings for nicotine, anger or irritability, anxiety, depression, impatience, trouble sleeping, restlessness (psychomotor agitation, including indeliberate movement), hunger or weight gain, and difficulty concentrating. Symptoms are usually strongest for the first few days and then dissipate over 2–4 weeks. The most common symptoms are irritability, anxiety, and difficulty concentrating. Depression and insomnia are the least common. Other withdrawal symptoms may include anhedonia, constipation, cough, decreased positive affect, dizziness, drowsiness, headache, impulsivity, fatigue, flu symptoms, mood swings, mouth ulcers, and increased dreaming. Cessation of nicotine can also require changes in levels of various medications. Nicotine withdrawal refers to the effects that nicotine-dependent individuals experience after they discontinue or decrease nicotine use. Nicotine is an addictive substance found most commonly in tobacco and tobacco products including cigarettes, cigars, chewing tobacco, e-cigarette liquid, pipe tobacco, snus, snuff, and nicotine medications such as nicotine gum. Withdrawal is the body’s reaction to not having the nicotine it had become accustomed to. Withdrawal is most common and intense in cigarette smokers and intermediate in smokeless and e-cigarette users.