A transport protein (variously referred to as a transmembrane pump, transporter, escort protein, acid transport protein, cation transport protein, or anion transport protein) is a protein that serves the function of moving other materials within an organism. Transport proteins are vital to the growth and life of all living things. There are several different kinds of transport proteins.
Carrier proteins are proteins involved in the movement of ions, small molecules, or macromolecules, such as another protein, across a biological membrane. Carrier proteins are integral membrane proteins; that is, they exist within and span the membrane across which they transport substances. The proteins may assist in the movement of substances by facilitated diffusion (i.e., passive transport) or active transport. These mechanisms of movement are known as carrier-mediated transport. Each carrier protein is designed to recognize only one substance or one group of very similar substances. Research suggests that potassium, calcium and sodium channels can function as oxygen sensors in mammals and plants, and has correlated defects in specific carrier proteins with specific diseases. A membrane transport protein (or simply transporter) is a membrane protein that acts as such a carrier.
A vesicular transport protein is a transmembrane or membrane associated protein. It regulates or facilitates the movement by vesicles of the contents of the cell.
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In cellular biology, active transport is the movement of molecules or ions across a cell membrane from a region of lower concentration to a region of higher concentration—against the concentration gradient. Active transport requires cellular energy to achieve this movement. There are two types of active transport: primary active transport that uses adenosine triphosphate (ATP), and secondary active transport that uses an electrochemical gradient.
This course introduces students to models of active and passive transport in biological systems. This will include the effect of external factors (motor proteins, crowding) and membrane dynamics on tr
Le TP de physiologie introduit les approches expérimentales du domaine biomédical, avec les montages de mesure, les capteurs, le conditionnement des signaux, l'acquisition et traitement de données.
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Le TP de physiologie introduit les approches expérimentales du domaine biomédical, avec les montages de mesure, les capteurs, le conditionnement des signaux, l'acquisition et traitement de données.
Le
Lipid membranes are complex and dynamic systems which are known to mediate signaling processes between cells and their environment. To do this multiple ion channels and pumps are involved in controlling the in- and out-flux of various ions (K+, Na+, Mg2+, ...
The past decades have seen the advent of information theory in various fields, from quantum physics to cosmology.At an intermediary scale between atomic and cosmological scales are biological systems and in particular the cell, as a constitutive element of ...
The serine protease prostasin (CAP1/Prss8, channel-activating protease-1) is a confirmed in vitro and in vivo activator of the epithelial sodium channel ENaC. To test whether proteolytic activity or CAP1/Prss8 abundance itself are required for ENaC activat ...