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Kinetic isotope effects for fast deuterium and proton exchange rates

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Geoffrey Bodenhausen, Daniele Mammoli, Estel Canet Martinez, Pavel Kaderavek
2016
journal articles

Abstract

By monitoring the effect of deuterium decoupling on the decay of transverse N-15 magnetization in D-N-15 spin pairs during multiple-refocusing echo sequences, we have determined fast D-D exchange rates k(D) and compared them with fast H-H exchange rates k(H) in tryptophan to determine the kinetic isotope effect as a function of pH and temperature.

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https://infoscience.epfl.ch/entities/publication/cb0cccd9-d064-4ddc-8531-f6d9f2474e83

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Nuclear magnetic resonance

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