Smooth structureIn mathematics, a smooth structure on a manifold allows for an unambiguous notion of smooth function. In particular, a smooth structure allows one to perform mathematical analysis on the manifold. A smooth structure on a manifold is a collection of smoothly equivalent smooth atlases. Here, a smooth atlas for a topological manifold is an atlas for such that each transition function is a smooth map, and two smooth atlases for are smoothly equivalent provided their union is again a smooth atlas for This gives a natural equivalence relation on the set of smooth atlases.
Hippocampal sclerosisHippocampal sclerosis (HS) or mesial temporal sclerosis (MTS) is a neuropathological condition with severe neuronal cell loss and gliosis in the hippocampus. Neuroimaging tests such as magnetic resonance imaging (MRI) and positron emission tomography (PET) may identify individuals with hippocampal sclerosis. Hippocampal sclerosis occurs in 3 distinct settings: mesial temporal lobe epilepsy, adult neurodegenerative disease and acute brain injury.