Clinical implementation of accelerated T-2 mapping: Quantitative magnetic resonance imaging as a biomarker for annular tear and lumbar disc herniation

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Multi-Scale Modeling Of Photopolymerization For Medical Hydrogel-Implant Design

Dominique Pioletti, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi, Salma Farahi

We report on the modeling of a photopolymerizable hydrogel and its application as a replacement of the interior of the intervertebral disc (so called Nucleus Pulposus). The hydrogel is initially injected in its liquid form and then photopolymerized via a s ...

Spie-Int Soc Optical Engineering2013

Damping properties of the nucleus pulposus

Dominique Pioletti, Arne Christian Vogel

Background: The nucleus pulposus is extremely deformable and it is not uncommon to observe strain amplitudes as large as 12.5% in physiological loading conditions. It has been shown that the nucleus pulposus contributes to the damping properties of the int ...

Elsevier2012

Biocomposite Hydrogels with Carboxymethylated, Nanofibrillated Cellulose Powder for Replacement of the Nucleus Pulposus

Pierre-Etienne Bourban, Ana Borges de Couraça, Fabien Duc

Biocomposite hydrogels with carboxymethylated, nanofibrillated cellulose (c-NFC) powder were prepared by UV polymerization of N-vinyl-2-pyrrolidone with Tween 20 trimethacrylate as a cross-linking agent for replacement of the native, human nucleus pulposus ...

American Chemical Society2011

Thermomechanical Hysteresis of Biological and Synthetic Hydrogels : Theory, Characterisation, and Development of a Novel Deformation Calorimeter

Arne Christian Vogel

The nucleus pulposus of the intervertebral disc is a gelatinous viscous hydrogel that has an essential role in the mechanics of the intervertebral disc joint. The viscoelastic properties of the nucleus pulposus significantly change in the course of time an ...

EPFL2011

Composite Hydrogels for the Replacement of the Nucleus Pulposus

Ana Borges de Couraça

The intervertebral disc (IVD), which provides flexibility to the spine and facilitates damping and motion, is composed of two distinct structures: the annulus fibrosus (AF) and the nucleus pulposus (NP). The AF, which is fibrous and elastic, confines the N ...

EPFL2010

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Thermomechanical Hysteresis of Biological and Synthetic Hydrogels : Theory, Characterisation, and Development of a Novel Deformation Calorimeter

Arne Christian Vogel

EPFL2011