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From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

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A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

Information is transmitted between brain regions through the release of neurotransmitters from long-range projecting axons. Understanding how the activity of such long-range connections contributes to behavior requires efficient methods for reversibly mani ...

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Curcuminoids and their complexes continue to attract attention in medicinal chemistry, but little attention has been given to their metabolic derivatives. Here, the first examples of (arene)Ru(II) complexes with curcuminoid metabolites, tetrahydrocurcumin ...

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Traditional cell cultures have long been fundamental to biological research, offering an alternative to animal models burdened by ethical constraints and procedural intricacies, often lacking relevance to human physiology and disease. Moreover, their inabi ...

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2024

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Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

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Cells are the smallest operational units of living systems. Through synthesis of various biomolecules and exchange of signals with the environment, cells tightly regulate their composition to realize a specific functional state. The transformation of a cel ...

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From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

Ru(II)-Arene Complexes of Curcumin and Bisdesmethoxycurcumin Metabolites

Metabolically enhanced CAR T cells efficiently clear solid tumors in mice

Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

Characterization of the gut-bone marrow axis through bile acid signaling

In vivo polydopamine coating of Rhodobacter sphaeroides for enhanced electron transfer

Subcortical correlates of consciousness with human single neuron recordings

Deciphering the nature of cell state transitions in single cells using quantitative modeling of temporal dynamics

Multimodal transcriptomic atlases of mouse spinal cord injury

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A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits

Ru(II)-Arene Complexes of Curcumin and Bisdesmethoxycurcumin Metabolites

Metabolically enhanced CAR T cells efficiently clear solid tumors in mice

Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

Characterization of the gut-bone marrow axis through bile acid signaling

In vivo polydopamine coating of Rhodobacter sphaeroides for enhanced electron transfer

Subcortical correlates of consciousness with human single neuron recordings

Deciphering the nature of cell state transitions in single cells using quantitative modeling of temporal dynamics

Multimodal transcriptomic atlases of mouse spinal cord injury

Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy

Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy