Publications related to Integrated field, laboratory, and theoretical study of PKD spread in a Swiss prealpine river

Effects of water releases and sediment supply on a residual flow reach

Giovanni De Cesare, Robin Schroff, Camille Blanck

An artificial floods program has been implemented on the Sarine residual flow reach, downstream of the Rossens dam. Two artificial floods were released in 2016 (coupled with sediment augmentation) and in 2020. A natural flood occurred in 2021. The indicato ...

CRC Press/Balkema2023

Evaluation of tire tread particle toxicity to fish using rainbow trout cell lines

Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset, Gabrielle Léger

Tire and road wear particles (TRWP) resulting from tire abrasion while driving raise concerns due to their potential contribution to aquatic toxicity. Our study aimed to assess cryogenically milled tire tread (CMTT) particle toxicity, used as a proxy for T ...

2023

Bioaccessibility of Organic Compounds Associated with Tire Particles Using a Fish In Vitro Digestive Model: Solubilization Kinetics and Effects of Food Coingestion

Kristin Schirmer, Florian Frédéric Vincent Breider, Dominique Grandjean, Benoît Jean Dominique Ferrari, Thibault Béranger Masset, Luke Christopher Harris

Tire and road wear particles (TRWP) account for an important part of the polymer particles released into the environment. There are scientific knowledge gaps as to the potential bioaccessibility of chemicals associated with TRWP to aquatic organisms. This ...

2022

Wirkungskontrolle einer Sedimentzugabe: Habitatvielfalt und Kolmation

Giovanni De Cesare, Christian Mörtl, Robin Schroff

In einer Restwasserstrecke der Saane wurde 2016 zur Sanierung der kolmatierten Gewässersohle und zur Aufwertung der Lebensräume ein künstliches Hochwasser ausgelöst und mit einer Sedimentzugabe gekoppelt. Die mittelfristigen Wirkungen der Sedimentzugabe wu ...

2021

In vitro acute toxicity assessment of tire tread particles using rainbow trout cell lines of gill and intestine

Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset

Tire and road wear particles (TRWP) are generated by the abrasion of tires while driving, and recent questions were raised in regards to their potential contribution to microplastics released into the aquatic environment and their potential toxicological i ...

2021

A ribonucleoprotein transfection strategy for CRISPR/Cas9-mediated gene editing and single cell cloning in rainbow trout cells

Kristin Schirmer

Background The advent of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 technology marked the beginning of a new era in the field of molecular biology, allowing the efficient and precise creation of targeted mutations in the ge ...

2021

Extending the Concept of Predicting Fish Acute Toxicity In Vitro to the Intestinal Cell Line RTgutGC

Kristin Schirmer, Hannah Inka Schug, Jenny Maner

Testing chemicals for fish acute toxicity is a legal requirement in many countries as part of environmental risk assessment. To reduce the number of fish used, substantial efforts have been focused on alternative approaches. Prominently, the cell viability ...

2020

Effects of altered river network connectivity on the distribution of Salmo trutta: Insights from a metapopulation model

Andrea Rinaldo, Enrico Bertuzzo, Luca Carraro, Alexia Maria Gonzalez Ferreras

Network connectivity is a key feature of rivers that affects patterns and processes in lotic ecosystems. Few studies have considered how changes in river reach connectivity might affect ecosystem attributes at a whole river network scale. The use of popula ...

WILEY2019

Fish-gut-on-chip: development of a microfluidic bioreactor to study the role of the fish intestine in vitro

Philippe Renaud, Kristin Schirmer, Sarah-Katharina Könemann, Carolin Drieschner

In this study we present the first fish-gut-on-chip model. This model is based on the reconstruction of the intestinal barrier by culturing two intestinal cell lines from rainbow trout, namely epithelial RTgutGC and fibroblastic RTgutF, in an artificial mi ...

2019

Percolation and Internet Science

Emanuele Massaro

Percolation, in its most general interpretation, refers to the “flow” of something (a physical agent, data or information) in a network, possibly accompanied by some nonlinear dynamical processes on the network nodes (sometimes denoted reaction–diffusion s ...

2019