Relevance (information retrieval)In information science and information retrieval, relevance denotes how well a retrieved document or set of documents meets the information need of the user. Relevance may include concerns such as timeliness, authority or novelty of the result. The concern with the problem of finding relevant information dates back at least to the first publication of scientific journals in the 17th century. The formal study of relevance began in the 20th Century with the study of what would later be called bibliometrics.
ToxicationToxication, toxification or toxicity exaltation is the conversion of a chemical compound into a more toxic form in living organisms or in substrates such as soil or water. The conversion can be caused by enzymatic metabolism in the organisms, as well as by abiotic chemical reactions. While the parent drug are usually less active, both the parent drug and its metabolite can be chemically active and cause toxicity, leading to mutagenesis, teratogenesis, and carcinogenesis.
