In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system

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Neuroscience robotics for controlled induction and real-time assessment of hallucinations

Olaf Blanke, Fosco Bernasconi, Jevita Potheegadoo, Herberto Dhanis Pedro De Barros Camacho, Giulio Rognini, Masayuki Hara, Eva Blondiaux, Laurent Frédéric Jenni

Although hallucinations are important and frequent symptoms in major psychiatric and neurological diseases, little is known about their brain mechanisms. Hallucinations are unpredictable and private experiences, making their investigation, quantification a ...

2022

Identification of biopsychological trait markers in functional neurological disorders

Serafeim Loukas

Weber et al. provide evidence in support of a stress-diathesis model of functional neurological disorders. They identify trauma history in the form of emotional neglect as a psychological risk factor, and reduced hippocampus and amygdala volume as a predis ...

OXFORD UNIV PRESS2022

Gait Variability to Phenotype Common Orthopedic Gait Impairments Using Wearable Sensors

Wei Zhang, Amir Muaremi

Mobility impairments are a common symptom of age-related degenerative diseases. Gait features can discriminate those with mobility disorders from healthy individuals, yet phenotyping specific pathologies remains challenging. This study aims to identify if ...

MDPI2022

Unsupervised Domain Adaptation for Cross-Subject Few-Shot Neurological Symptom Detection

Mahsa Shoaran, Bingzhao Zhu

Modern machine learning tools have shown promise in detecting symptoms of neurological disorders. However, current approaches typically train a unique classifier for each subject. This subject-specific training scheme requires long labeled recordings from ...

IEEE2021

Designing Gamified Activities with Haptic-Enabled Tangible Robots for Therapy and Assistance

Arzu Güneysu Özgür

In this thesis, we contribute to the field of rehabilitation robotics by designing haptic-enabled tangible robot-based activities and exploring their added value for therapy and assistance. The research specifically focuses on the design and development of ...

EPFL2021

A modular strategy for next-generation upper-limb sensory-motor neuroprostheses

Silvestro Micera, Solaiman Shokur, Giuseppe Schiavone

Neuroprosthetics is a discipline that aims at restoring lost functions to people affected by a variety of neurological disorders or neuro-traumatic lesions. It combines the expertise of computer science and electrical, mechanical, and micro/nanotechnology ...

ELSEVIER2021

Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders

Andreas Rowald

Spinal Cord Injury (SCI) disrupts the communication between the brain and spinal circuits below the lesion, leading to a plethora of neurological impairments, including the loss of motor function. At present, the only medical practices to enhance recovery ...

EPFL2021

Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders

Robin Jonathan Demesmaeker

Neurological disorders such as spinal cord injury (SCI) massively reduce independence and quality of life. Most often, the majority of the nervous system is still fully or partially spared, but dysfunctional due to aberrant or absent descending input from ...

EPFL2021

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Diego Ghezzi, Philippe Reymond, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

Development of a peripheral neuroprosthesis to elicit fine hand movements in primates

Marion Aimée Geneviève Badi-Dubois

Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...

EPFL2021

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Personalizable computational models of electrical spinal cord stimulation to restore function after neurological disorders

Andreas Rowald

EPFL2021

Development of a peripheral neuroprosthesis to elicit fine hand movements in primates

Marion Aimée Geneviève Badi-Dubois

EPFL2021

Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders

Robin Jonathan Demesmaeker

EPFL2021