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High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

Related publications (31)

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

EPFL2023

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Alessia De Masi

The natural compound Cyclo Histidine-Proline (CHP) was initially discovered in the brain, but thereafter evaluated in the context of diabetes because of its hypoglycemic action. The pharmacokinetics and the toxicological profile of CHP showed it can be dos ...

EPFL2023

Lessons on brain edema in HE: from cellular to animal models and clinical studies

Cristina Ramona Cudalbu, Katarzyna Pierzchala, Jessie Julie Mosso

Brain edema is considered as a common feature associated with hepatic encephalopathy (HE). However, its central role as cause or consequence of HE and its implication in the development of the neurological alterations linked to HE are still under debate. I ...

SPRINGER/PLENUM PUBLISHERS2023

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Felix Naef, Tomaz Martini

Hepatocytes are the main workers in the hepatic factory, managing metabolism of nutrients and xenobiotics, production and recycling of proteins, and glucose and lipid homeostasis. Division of labor between hepatocytes is critical to coordinate complex comp ...

ANNUAL REVIEWS2023

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

Henning Paul-Julius Stahlberg, Dongchun Ni

BSEP (ABCB11) is an ATP-binding cassette transporter that is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. BSEP dysfunction, caused by mutations or induced by drugs, is frequently associated with severe cholestatic live ...

Nature Portfolio2023

NMR Crystallography in the Big Data Era: New Methods and Applications Powered by Machine Learning

Manuel Cordova

Structure determination of materials is key to understanding their physical properties. While single-crystal X-ray diffraction is the gold standard for structures displaying long-range order, many materials of interest are polycrystalline and/or disordered ...

EPFL2023

Fast, Broad-Band Magnetic Resonance Spectroscopy with Diamond Widefield Relaxometry

Mayeul Sylvain Chipaux, Hoda Shirzad

We present an alternative to conventional Electron the use of bulky magnets and magnetron equipment, we use the photoluminescence of an ensemble of Nitrogen-Vacancy centers at the surface of a diamond. Monitoring their relaxation time (or T1), we detected ...

AMER CHEMICAL SOC2023

Cost-effective equalization of electro-optic frequency combs in a Sagnac interferometer

Camille Sophie Brès, Jianqi Hu, Ivan Cardea

We present a cost-effective electro-optic frequency comb generation and equalization method using a single phase modulator inserted in a Sagnac interferometer layout. The equalization relies on the interference of comb lines generated in both clockwise and ...

Optica Publishing Group2023

Investigating the Effect of Crystal Morphology on Optoelectronic Properties of Zinc Phosphide Thin Films via Optical-pump Terahertz Probe Spectroscopy

Elias Zsolt Stutz, Jean-Baptiste Leran, Mahdi Zamani, Rajrupa Paul, Simon Robert Escobar Steinvall, Mirjana Dimitrievska, Léa Buswell

Zinc phosphide ( Zn3P2) is a promising earth-abundant material for solar cell applications but calls for the further understanding of its optoelectronic properties. In this work, we perform contact-free and noninvasive optical-pump terahertz probe (OPTP) s ...

IEEE2023

High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Lessons on brain edema in HE: from cellular to animal models and clinical studies

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

NMR Crystallography in the Big Data Era: New Methods and Applications Powered by Machine Learning

Fast, Broad-Band Magnetic Resonance Spectroscopy with Diamond Widefield Relaxometry

Cost-effective equalization of electro-optic frequency combs in a Sagnac interferometer

Investigating the Effect of Crystal Morphology on Optoelectronic Properties of Zinc Phosphide Thin Films via Optical-pump Terahertz Probe Spectroscopy

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New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Lessons on brain edema in HE: from cellular to animal models and clinical studies

Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology

Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP

NMR Crystallography in the Big Data Era: New Methods and Applications Powered by Machine Learning

Fast, Broad-Band Magnetic Resonance Spectroscopy with Diamond Widefield Relaxometry

Cost-effective equalization of electro-optic frequency combs in a Sagnac interferometer

Investigating the Effect of Crystal Morphology on Optoelectronic Properties of Zinc Phosphide Thin Films via Optical-pump Terahertz Probe Spectroscopy

Longitudinal incremental propensity score interventions for limited resource settings

Longitudinal incremental propensity score interventions for limited resource settings