Publications related to Adaptive optics enables multimode 3D super-resolution microscopy via remote focusing

A Cavity-Microscope for Quantum Simulations with Locally-Controllable All-to-All Interactions

This thesis presents the development, construction, and benchmark of an experimental platform that combines cold fermionic 6Li atoms with locally controllable light-matter interactions. To enable local control, a new device, the cavity-microscope, was crea ...

EPFL2024

Compact and effective photon-resolved image scanning microscope

Giorgio Tortarolo

Fluorescence confocal laser-scanning microscopy (LSM) is one of the most popular tools for life science research. This popularity is expected to grow thanks to single-photon array detectors tailored for LSM. These detectors offer unique single-photon spati ...

Spie-Soc Photo-Optical Instrumentation Engineers2024

On the Generalization of Stochastic Gradient Descent with Momentum

Volkan Cevher, Kimon Antonakopoulos

While momentum-based accelerated variants of stochastic gradient descent (SGD) are widely used when training machine learning models, there is little theoretical understanding on the generalization error of such methods. In this work, we first show that th ...

Microtome Publishing2024

Ghost imaging using two SPAD array detectors: a parameter study towards the realization of a 3D quantum microscope

Edoardo Charbon, Claudio Bruschini, Paul Mos, Yang Lin

Quantum ghost imaging can be an important tool in making optical measurements. One of the most useful aspects of ghost imaging is the unique ability to correlate two sets of independently collected information. We aim to use the principles of ghost imaging ...

Spie-Int Soc Optical Engineering2024

Live-cell imaging powered by computation

Suliana Manley, Florian Jug

The proliferation of microscopy methods for live-cell imaging offers many new possibilities for users but can also be challenging to navigate. The prevailing challenge in live-cell fluorescence microscopy is capturing intra-cellular dynamics while preservi ...

Nature Portfolio2024

A study of the K^(+) → π^(0)e^(+)νγ decay

Alessandro Mapelli, Alina Kleimenova, Radoslav Marchevski

A sample of 1.3 x 10^(5) K^(+) → π^(0)e^(+)νγ candidates with less than 1% background was collected by the NA62 experiment at the CERN SPS in 2017-2018. Branching fraction measurements are obtained at percent relative precision in three restricted kinemati ...

Springer Nature2023

Chemical Probe for Imaging of Polo-like Kinase 4 and Centrioles

Kai Johnsson, Pierre Gönczy, Luc Reymond, Georgios Hatzopoulos, Aleksandar Salim

Polo-like kinase (Plk4) is a serine/threonine-proteinkinase thatis essential for biogenesis of the centriole organelle and is enrichedat centrioles. Herein, we introduce Cen-TCO, a chemical probe basedon the Plk4 inhibitor centrinone, to image Plk4 and cen ...

AMER CHEMICAL SOC2023

Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysis

Maria del Carmen Sandi Perez, Mandy Meijer

DNA methylation (DNAm) is one of the most frequently studied epigenetic mechanisms facilitating the interplay of genomic and environmental factors, which can contribute to externalizing behaviours and related psychiatric disorders. Previous epigenome-wide ...

PERGAMON-ELSEVIER SCIENCE LTD2023

Epidemic Learning: Boosting Decentralized Learning with Randomized Communication

Rachid Guerraoui, Anne-Marie Kermarrec, Sadegh Farhadkhani, Rafael Pereira Pires, Rishi Sharma, Marinus Abraham de Vos

We present Epidemic Learning ( EL ), a simple yet powerful decentralized learning (DL) algorithm that leverages changing communication topologies to achieve faster model convergence compared to conventional DL approaches. At each round of EL, each node sen ...

2023

Time-Resolved Scanning Ion Conductance Microscopy and Single-Molecule Spectroscopy

Samuel Mendes Leitão

The evolution of the 3D morphology is at the center of many relevant biological processes ranging from cellular differentiation to cancer invasion and metastasis. Microscopy techniques, such as electron microscopy (EM), super-resolution (SR) optical micros ...

EPFL2023