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Plasma biomarkers for Alzheimer's disease: a field-test in a memory clinic

Related publications (30)

Nanoparticle-enhanced Imaging Based Plasmonic Biosensor

Efficient medical care fundamentally relies on the ability to provide a timely and accurate diagnosis. Thanks to advances in biomedical research, specific molecules called diagnostic molecular biomarkers have been discovered in the human body that help ind ...

EPFL2020

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Rolf Gruetter, Anders Meibom, Graham Knott, Bernard Lanz, Stéphane Laurent Escrig, Nadine Fournier, Mario Gaetano Lepore, Etienne Meylan, Louise Helene Soegaard Jensen, Caroline Anne-Lyse Contat

Glucose utilization increases in tumors, a metabolic process that is observed clinically by F-18-fluorodeoxyglucose positron emission tomography (F-18-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are impl ...

2020

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Application of virtual reality in neurosurgery: Patient missing. A systematic review

Olaf Blanke, Bruno Herbelin

Virtual reality (VR) technology had its earliest developments in the 1970s in the U.S. Air Force and has since evolved into a budding area of scientific research with many practical medical purposes. VR shows a high potential to benefit to learners and tra ...

2021

Nanoparticle-enhanced Imaging Based Plasmonic Biosensor

Alexander Belushkin

EPFL2020

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Rolf Gruetter, Anders Meibom, Graham Knott, Bernard Lanz, Stéphane Laurent Escrig, Nadine Fournier, Mario Gaetano Lepore, Etienne Meylan, Louise Helene Soegaard Jensen, Caroline Anne-Lyse Contat

2020

Noninvasive detection of focal seizures in ambulatory patients

David Atienza Alonso, Leila Cammoun

Reliably detecting focal seizures without secondary generalization during daily life activities, chronically, using convenient portable or wearable devices, would offer patients with active epilepsy a number of potential benefits, such as providing more re ...

2020

Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies

Andrea Pfeifer

The compound screening was initiated with a direct staining assay to identify compounds binding to Tau aggregates and not Abeta plaques using human brain sections derived from late stage Alzheimer's disease donors. The binding of Tau aggregate selective co ...

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER2020

Multidisciplinary Approach to Treat Erectile Dysfunction

Mikaël Nils Sturny

Erectile dysfunction (ED) is a widespread disease affecting approximately 20% of men. With a rising incidence due to the global ageing of the world population, it is estimated that over 322 million patients will be affected in 2025. While not being a lifet ...

EPFL2020

Novel PDE6B Mutation Presenting with Retinitis Pigmentosa - A Case Series of Three Patients

Imen Habibi

Background Retinitis pigmentosa (RP) affects 2.5 million people worldwide. Increased identification of causative gene defects and the increasing possibility of treatment necessitates better knowledge of phenotype-genotype correlations to help identify pati ...

2019

A nation-wide initiative for brain imaging and clinical phenotype data federation in Swiss university memory centres

Jean-Philippe Thiran, Bogdan Draganski

Purpose of review ...

LIPPINCOTT WILLIAMS & WILKINS2019

Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay

Hilal Lashuel, Sean Michael Deguire, Lara Petricca

Accumulation and aggregation of misfolded alpha-synuclein is believed to be a cause of Parkinson's disease (PD). Phosphorylation of alpha-synuclein at S129 is known to be associated with the pathological misfolding process, but efforts to investigate the r ...

2019

Rapid and Digital Detection of Inflammatory Biomarkers Enabled by a Novel Portable Nanoplasmonic Imager

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

New point-of-care diagnostic devices are urgently needed for rapid and accurate diagnosis, particularly in the management of life-threatening infections and sepsis, where immediate treatment is key. Sepsis is a critical condition caused by systemic respons ...

2019

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Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies

Andrea Pfeifer

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER2020

Rapid and Digital Detection of Inflammatory Biomarkers Enabled by a Novel Portable Nanoplasmonic Imager

Hatice Altug, Filiz Yesilköy, Alexander Belushkin

2019

A nation-wide initiative for brain imaging and clinical phenotype data federation in Swiss university memory centres

Jean-Philippe Thiran, Bogdan Draganski

Purpose of review ...

LIPPINCOTT WILLIAMS & WILKINS2019

Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay

Hilal Lashuel, Sean Michael Deguire, Lara Petricca

2019