Under broad assumptions, breaking of Lorentz invariance in gravitational theories leads to tension with unitarity because it allows for processes that apparently violate the second law of thermodynamics. The crucial ingredient of this argument is the exist ...
Sirt1 is an NAD1-dependent deacetylase that extends lifespan in lower organisms and improves metabolism and delays the onset of age-related diseases in mammals. Here we show that SRT1720, a synthetic compound that was identified for its ability to activate ...
Horava's proposal for non-relativistic quantum gravity introduces a preferred time foliation of space-time which violates the local Lorentz invariance. The foliation is encoded in a dynamical scalar field which we call 'khronon'. The dynamics of the khrono ...
Telomerase is required for telomere maintenance and is responsible for the immortal phenotype of cancer cells. How telomerase is assembled and reaches telomeres in the context of nuclear architecture is not understood. Recently, the telomerase RNA subunit ...
Telomerase is the ribonucleoprotein enzyme that elongates telomeres to counteract telomere shortening. The core enzyme consists of a reverse transcriptase protein subunit and an RNA subunit. The RNA subunit contains a short region that is used as a templat ...
