Generating High Fidelity Surface Meshes of Neocortical Neurons using Skin Modifiers

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Microfluidic devices for automated analysis of ingested bacteria in the Caenorhabditis elegans intestine

Farzad Rezaeianaran

In this thesis, we explored on-chip high-resolution imaging of the fate of intestinal bacteria and bacterial products in Caenorhabditis elegans (C. elegans). In the first part, we carried out high-resolution z-stack fluorescent imaging of Red Fluorescent P ...

EPFL2023

Digital reconstruction of the mammalian spinal cord: from anatomical reference volume to cell type atlas of the mouse spinal cord

Ihor Kuras

The spinal cord is an elongated nervous structure that together with the brain forms the central nervous system. It relays sensory and motor information between the brain and the body, thus controlling most somatic and autonomic body functions. In recent y ...

EPFL2023

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Polina Shichkova

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

Meshing of Spiny Neuronal Morphologies using Union Operators

Felix Schürmann, Marwan Muhammad Ahmed Abdellah, Elvis Boci, Nadir Roman Guerrero, Juan José García Cantero, Alessandro Enrico Foni

Neurons are characterized by thin and long interleaving arborizations in which creating accurate mesh models of their cellular membranes is challenging. While union operators are central for CAD/CAM modeling and computer graphics applications, their applic ...

2022

Synthesis and Analysis of 3D shapes with Geometric Deep Learning in Computer-Aided Engineering

Edoardo Remelli

In this thesis, we advocate that Computer-Aided Engineering could benefit from a Geometric Deep Learning revolution, similarly to the way that Deep Learning revolutionized Computer Vision. To do so, we consider a variety of Computer-Aided Engineering pr ...

EPFL2022

Differentiable Signed Distance Function Rendering

Wenzel Alban Jakob, Delio Aleardo Vicini, Sébastien Nicolas Speierer

Physically-based differentiable rendering has recently emerged as an attractive new technique for solving inverse problems that recover complete 3D scene representations from images. The inversion of shape parameters is of particular interest but also pose ...

ASSOC COMPUTING MACHINERY2022

Geometrical Treatise on the Modelling of 3D Particulate Inclusion-Matrix Microstructures with an Application to Historical Stone Masonry Walls

Mahmoud S. M. Shaqfa

As historical stone masonry structures are vulnerable and prone to damage in earthquakes, investigating their structural integrity is important to reduce injuries and casualties while preserving their historical value. Stone masonry is a composite material ...

EPFL2022

A virtual microstructure generator for 3D stone masonry walls

Katrin Beyer, Mahmoud S. M. Shaqfa

Detailed micromodel simulations of stone masonry walls require as input a 3D mesh that represents a realistic arrangement of stones in the masonry wall. In this paper, we constructed the first 3D masonry microstructures to derive 2D and 3D finite or discre ...

ELSEVIER2022

An a posteriori error estimator for isogeometric analysis on trimmed geometries

Annalisa Buffa, Rafael Vazquez Hernandez, Ondine Gabrielle Chanon

Trimming consists of cutting away parts of a geometric domain, without reconstructing a global parametrization (meshing). It is a widely used operation in computer-aided design, which generates meshes that are unfitted with the described physical object. T ...

2022

Differentiable Physically Based Rendering: Algorithms, Systems and Applications

Merlin Eléazar Nimier-David

Physically based rendering methods can create photorealistic images by simulating the propagation and interaction of light in a virtual scene. Given a scene description including the shape of objects, participating media, material properties, etc., the sim ...

EPFL2022

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Microfluidic devices for automated analysis of ingested bacteria in the Caenorhabditis elegans intestine

Farzad Rezaeianaran

EPFL2023

Digital reconstruction of the mammalian spinal cord: from anatomical reference volume to cell type atlas of the mouse spinal cord

Ihor Kuras

EPFL2023

Geometrical Treatise on the Modelling of 3D Particulate Inclusion-Matrix Microstructures with an Application to Historical Stone Masonry Walls

Mahmoud S. M. Shaqfa

EPFL2022