Publication

Contribution of polymeric materials to progress in xenotransplantation of microencapsulated cells - A review

Publications associées (23)

Biocompatible and Biodegradable 3D Printing from Bioplastics: A Review

There has been a lot of interest in developing and producing biodegradable polymers to address the current environmental problem caused by the continued usage of synthetic polymers derived from petroleum products. Bioplastics have been identified as a poss ...

MDPI2023

Phase behaviour and structure of a model biomolecular condensate

Julian Charles Shillcock

Phase separation of immiscible fluids is a common phenomenon in polymer chemistry, and is recognized as an important mechanism by which cells compartmentalize their biochemical reactions. Biomolecular condensates are condensed fluid droplets in cells that ...

2020

Functional and Responsive Polymers via Controlled Radical Polymerization

Jian Wang

This Thesis is built around 4 topics, which share in common that they all take advantage of the assets of controlled radical polymerization to either (i) prepare well-defined model systems to address fundamental research questions with regard to the sensit ...

EPFL2020

Development of functionalized alginate-based hydrogels to reduce fibrosis in the transplantation of microencapsulated cells

François Rémi Pierre Noverraz

Nowadays, the development of cell therapy relies mainly on the advances made toward cell microencapsulation which allows to evade the need for immunosuppression during cell transplantation. Among the materials considered for cell encapsulation, hydrogels d ...

EPFL2018

Polymer-theory insights into biomolecular systems

Salvatore Assenza

Boosted by the technological advances in experimental techniques, cellular biology is nowadays facing the need for quantitative approaches in order to rationalize the huge amount of collected data. A particularly succesfull theoretical framework is provide ...

EPFL2015

Peptide-Polymer Conjugates for Therapeutic Applications

Ana Maria Raduta

Over the last ten years the attention of the pharmaceutical industry has shifted away from small molecules to focus on new biologics such as antibodies, proteins and therapeutic peptides. Herein, peptides have emerged as a particularly interesting category ...

EPFL2015

Cell Compatible Arginine Containing Cationic Polymer: One-Pot Synthesis and Preliminary Biological Assessment

Lucia Baldi Unser, Jutta Christine Wandrey, Xiao Shen, Nino Zavradashvili, Tamar Memanishvili

Synthetic cationic polymers are of interest as both nonviral vectors for intracellular gene delivery and antimicrobial agents. For both applications synthetic polymers containing guanidine groups are of special interest since such kind of organic compounds ...

Springer India2014

Squaric acid mediated bioconjugation expanded to polymers prepared by ATRP

Harm-Anton Klok, Frederik Roman Wurm

The squaric acid mediated bioconjugation reaction is an attractive approach for the amine-selective protein modification with side-chain functional polymers. This manuscript presents 3 squaric acid based atom transfer radical polymerization (ATRP) initiato ...

Royal Soc Chemistry2014

Squaric Acid Mediated Synthesis and Biological Activity of a Library of Linear and Hyperbranched Poly(Glycerol)-Protein Conjugates

Harm-Anton Klok, Frederik Roman Wurm

Polymer-protein conjugates generated from side chain functional synthetic polymers are attractive because they can be easily further modified with, for example, labeling groups or targeting ligands. The residue specific modification of proteins with side c ...

American Chemical Society2012

Hybrid Polymer Foams for Osteochondral Tissue Engineering

Matthieu Cuénoud

Articular cartilage is a soft tissue that covers the ends of articulating bones, and is essential for maintaining joint motion, i.e. translation and rotation between the bones. Articular cartilage nevertheless has a limited capacity for self-repair, and ca ...

EPFL2012