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The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

Publications associées (29)

How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior

The bacterium Vibrio cholerae is the causative agent of the diarrheal disease cholera, which affects millions of people every year. Apart from being a human pathogen, V. cholerae is also a common member of aquatic habitats. Whilst the mechanism that allow ...

EPFL2022

Engineering synthetic adhesins for biophysical investigation and rewiring of host-microbe interactions

Xavier Jean-Yves Pierrat

Host attachment is often a critical step in the onset of pathogenesis. To attach to host cells, bacteria have evolved a range of adhesins that bind to specific receptors. Some of these adhesins have been thoroughly characterized using biochemical technique ...

EPFL2022

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

Melanie Blokesch, David William Adams, Milena Jadwiga Jaskolska

Horizontal gene transfer can trigger rapid shifts in bacterial evolution. Driven by a variety of mobile genetic elements—in particular bacteriophages and plasmids—the ability to share genes within and across species underpins the exceptional adaptability o ...

2022

Warping-Inclusive Kinematic Coupling in Mixed-Dimension Macro Models for Steel Wide Flange Beam Columns

Dimitrios Lignos, Albano António De Abreu E Presa De Castro E Sousa, Alexander Riley Hartloper

A warping-inclusive kinematic coupling method to be used in finite-element analysis of members featuring wide-flange cross sections is proposed in this paper. This coupling method is used in mixed-dimension macromodels that combine continuum and beam-colum ...

2022

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

Melanie Blokesch, Nina Vesel

Acinetobacter baumannii is a severe threat to human health as a frequently multidrug-resistant hospital-acquired pathogen. Part of the danger from this bacterium comes from its genome plasticity and ability to evolve quickly by taking up and recombining ex ...

American Society for Microbiology2021

The molecular treasure box of environmental Vibrio cholerae strains

Natalia Carolina Drebes Dorr

Cholera pandemics have been affecting humankind for centuries and are still considered a major public health problem, especially in regions around the world with poor access to clean water and sanitation. Cholera pandemics are caused by a specific lineage ...

EPFL2021

Coupling-dependent convergence behavior of phase oscillators with tegotae-control

Auke Ijspeert, Jonathan Patrick Arreguit O'Neill, Simon Lukas Hauser, Matthieu Guillaume Marie Dujany

A bio-inspired way to model locomotion is using a network of coupled phase oscillators to create a Central Pattern Generator (CPG). The recently developed feedback control method tegotae includes exteroceptive force feedback into the governing phase update ...

IEEE2021

Biofilms deform soft surfaces and disrupt epithelia

Alexandre Louis André Persat, Alice Cont, Tamara Rossy

During chronic infections and in microbiota, bacteria predominantly colonize their hosts as multicellular structures called biofilms. A common assumption is that biofilms exclusively interact with their hosts biochemically. However, the contributions of me ...

2020

Comparison of chitin‐induced natural transformation in pandemic Vibrio cholerae O1 El Tor strains

Melanie Blokesch, Sandrine Stutzmann

The human pathogen Vibrio cholerae serves as a model organism for many important processes ranging from pathogenesis to natural transformation, which has been extensively studied in this bacterium. Previous work has deciphered important regulatory circuits ...

2020

The type IV pilus protein PilU functions as a PilT-dependent retraction ATPase

How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior

Engineering synthetic adhesins for biophysical investigation and rewiring of host-microbe interactions

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

Warping-Inclusive Kinematic Coupling in Mixed-Dimension Macro Models for Steel Wide Flange Beam Columns

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

The molecular treasure box of environmental Vibrio cholerae strains

Coupling-dependent convergence behavior of phase oscillators with tegotae-control

Biofilms deform soft surfaces and disrupt epithelia

Comparison of chitin‐induced natural transformation in pandemic Vibrio cholerae O1 El Tor strains

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How Vibrio cholerae adapts to the environment: from cell shape transitions to antagonistic behavior

Engineering synthetic adhesins for biophysical investigation and rewiring of host-microbe interactions

Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae

Warping-Inclusive Kinematic Coupling in Mixed-Dimension Macro Models for Steel Wide Flange Beam Columns

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

The molecular treasure box of environmental Vibrio cholerae strains

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation

Coupling-dependent convergence behavior of phase oscillators with tegotae-control

Biofilms deform soft surfaces and disrupt epithelia

Comparison of chitin‐induced natural transformation in pandemic Vibrio cholerae O1 El Tor strains

Structural Basis of Ligand Selectivity by a Bacterial Adhesin Lectin Involved in Multispecies Biofilm Formation