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This lecture explores the biochemistry of fear, focusing on the brain regions involved in the fear response and the neurotransmitters responsible for processing fear. It delves into the role of the amygdala, thalamus, hippocampus, and prefrontal cortex in interpreting perceived threats, as well as the release of stress hormones like adrenaline and cortisol. The rush of adrenaline during the fight-or-flight response is also discussed, along with the involvement of neurotransmitters like glutamate, serotonin, and GABA. The lecture concludes by examining the impact of fear on physiological responses such as increased heart rate and blood pressure.