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This lecture covers the ethical considerations in research involving human subjects, focusing on topics such as research in humans, ethical issues of research on biological material, genome editing controversies, and the establishment of biobanks for personalized medicine. It delves into the historical development of research ethics, including the Nuremberg Code and the Belmont Report, and discusses the importance of obtaining informed consent, respecting autonomy, and protecting vulnerable populations. The lecture also explores the case of Henrietta Lacks and the ethical implications of using human biological material for research purposes.