This lecture covers the evolution of brain region atlases through connectivity-based parcellation, including cluster formation, cluster characterization, and seed voxel clustering. It discusses stable solutions across filter sizes, distance measures, and cluster algorithms, as well as the merging of different meta-analyses and spectral reordering. The instructor presents the connectivity-based parcellation of the TPJ network, forward and reverse inference, and criteria for cluster formation, such as topology, information theory, and separation.