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This lecture covers the key principles of antigen recognition by T cells, focusing on how the immune system ensures that a specific antigen finds its corresponding T cell. It explains the process of antigen capture by antigen-presenting cells, the functions of different antigen-presenting cells, and the mechanisms of MHC class I and II processing and presentation. The lecture also discusses the immunogenicity of protein antigens, the presentation of nonprotein antigens to T cells, and the response of T cells to superantigens.
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