Human spaceflightHuman spaceflight (also referred to as manned spaceflight or crewed spaceflight) is spaceflight with a crew or passengers aboard a spacecraft, often with the spacecraft being operated directly by the onboard human crew. Spacecraft can also be remotely operated from ground stations on Earth, or autonomously, without any direct human involvement. People trained for spaceflight are called astronauts (American or other), cosmonauts (Russian), or taikonauts (Chinese); and non-professionals are referred to as spaceflight participants or spacefarers.
Human presence in spaceHuman presence in space is about humanity in space, particularly about all anthropogenic presence in space and human activity in space, that is in outer space and in a broader sense also on any extraterrestrial astronomical body. Humans have been present in space either, in the common sense, through their direct presence and activity like human spaceflight, or through mediation of their presence and activity like with uncrewed spaceflight, making "telepresence" possible.
Human spaceflight programsHuman spaceflight programs have been conducted, started, or planned by multiple countries and companies. The age of manned rocket flight was initiated by Fritz von Opel who piloted the world's first rocket-propelled flight on 30 September 1929. All space flights depend on rocket technology; von Opel was the co-designer and financier of the visionary project. Until the 21st century, human spaceflight programs were sponsored exclusively by governments, through either the military or civilian space agencies.
Outer spaceOuter space, commonly referred to simply as space, is the expanse that exists beyond Earth and its atmosphere and between celestial bodies. Outer space is not completely empty; it is a near-perfect vacuum containing a low density of particles, predominantly a plasma of hydrogen and helium as well as electromagnetic radiation, magnetic fields, neutrinos, dust, and cosmic rays. The baseline temperature of outer space, as set by the background radiation from the Big Bang, is .
Effect of spaceflight on the human bodyVenturing into the environment of space can have negative effects on the human body. Significant adverse effects of long-term weightlessness include muscle atrophy and deterioration of the skeleton (spaceflight osteopenia). Other significant effects include a slowing of cardiovascular system functions, decreased production of red blood cells (space anemia), balance disorders, eyesight disorders and changes in the immune system.