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This lecture by the instructor covers the role of mitochondrial Hsp70 in the import and folding of proteins. It discusses the translocation of proteins into different mitochondrial compartments, the interaction of Hsp70 with various complexes, and the implications of mtHsp70 distribution. The lecture also explores stress response pathways related to impaired mitochondrial protein import and the mitochondrial unfolded protein response. Additionally, it delves into experimental techniques used to study mtHsp70 conformation and protein import in mitochondria.