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This lecture delves into Newton's 30 years of research in alchemy, exploring his laboratory records, techniques, and influences from figures like Robert Boyle. It discusses Boyle's experiments, alchemical principles, and Newton's reenactment of them. The identity of the liquor of antimony is scrutinized, along with Newton's meticulous approach to experiments. The lecture concludes by highlighting the challenges in deciphering Newton's notebooks and the necessity of replicating his experiments to understand his thought process.