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This lecture covers the determination of the diffusion coefficient in gases, liquids, and solids using the Matano method and the general theory of random motion. It explains the influence of parameters such as temperature, molecular weight, and molar fraction on diffusion. The lecture also delves into the diffusion process in different states of matter, including gases, liquids, and crystalline solids, highlighting the role of intermolecular forces and viscosity. Additionally, it explores the random movement of particles and the factors affecting diffusion in crystalline solids. Practical examples and equations are provided to illustrate the concepts discussed.