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This lecture covers the major neurotransmitters in the brain, including acetylcholine, catecholamines, and serotonin. It explains their mode of action, major receptors, and the effects of drugs that stimulate them. The lecture also delves into the use of cholinesterase inhibitors in Alzheimer's disease, the role of beta-blockers in PTSD, and the involvement of glutamate in Long-Term Potentiation (LTP). Additionally, it discusses the effects of neurotransmitters on mood regulation, cognitive enhancement, and drug therapy. The presentation provides insights into the mechanisms of action of various neurotransmitter receptors and their impact on brain function.