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This lecture explores the intersection between science and politics, highlighting how sociotechnical controversies are embedded in power relations and conflicts over empirical evidence, standards, and research agendas. It delves into the disruptive nature of science and technology entities, their effects on society, and the emergence of new political issues and public controversies. The discussion extends to the implications for sovereignty, the role of procedures in managing scientific problems, and the influence of institutions on political dynamics. Through various examples, the instructor emphasizes the need to understand the political dimensions of science and technology to navigate the complexities of contemporary society.