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This lecture covers the influence of temperature, pressure, and crystalline structure on self-diffusion in metals. It discusses the quantification of diffusion coefficients, the impact of atomic jumps and enthalpy on diffusion, and the role of crystal structures. The lecture also explores the Arrhenius equation, intrinsic defects, and the pressure effect on diffusion mechanisms. Additionally, it delves into the energy balance required for atomic jumps and the different crystal structures affecting diffusion rates.