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This lecture introduces the importance of numerical methods in biomechanics, focusing on analyzing observations, testing hypotheses, and improving medical devices and treatments. It covers the advantages and drawbacks of numerical methods, the trend towards integration in multi-scale and multi-physics approaches, and the course objectives, content, and evaluation criteria. The lecture also discusses exercises with COMSOL, the midterm test, group projects related to biomechanics, and mini-project suggestions and examples. It emphasizes the application of numerical modeling in various biomechanical scenarios and provides resources for project articles.