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This lecture covers the integration of hydro-electrolyte homeostasis by hormones, focusing on the hormonal control of sodium and potassium pools, renal physiology, and factors regulating the secretion of aldosterone and renin. It also discusses the mechanism of action and effects of aldosterone, potassium intake, distribution in the body, and routes of excretion. The lecture delves into the normal values of sodium intake, distribution, and excretion, as well as the impact of aldosterone on potassium secretion and the renal system.