Lecture

RNA Switches: Design & Applications

Description

This lecture delves into the design and applications of RNA switches, exploring the principles of regulatory RNAs to engineer new biomolecular components with diverse functionalities. Topics covered include the structure of eukaryotic mRNA, translational control mechanisms, riboregulators, ribozymes, riboswitches, and ligand-guided RNA-conformational gating. The lecture also discusses the engineering of RNA molecules with new biological functions and applications, emphasizing the hijacking of natural regulatory RNA principles. Various case examples are presented, showcasing the development of engineered RNA-based gene regulatory tools. The session concludes with a focus on positive and negative selection in enzyme evolution and key take-home points.

This video is available exclusively on Mediaspace for a restricted audience. Please log in to MediaSpace to access it if you have the necessary permissions.

Watch on Mediaspace
About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.