Drug Delivery: Nanoparticles and Biomaterials

This lecture covers the design parameters for targeting therapy, including size, shape, charge, ligand density, and receptor expression levels. It discusses the design of nanomaterials such as antibodies, proteins, and polymers, focusing on surface chemistry and functionality. The lecture also explores natural barriers to drug delivery, stimuli responsiveness in drug release, and engineering possibilities for drug delivery systems. It delves into stimuli-responsive drug delivery systems in clinical trials and concludes by emphasizing the importance of understanding targeting, release mechanisms, and toxicity levels in developing new therapeutics.