This lecture presents the Envirobot project, aiming to develop a robot capable of detecting and locating pollutants in aquatic environments. The robot is equipped with miniaturized sensors for physical, chemical, and biological measurements, allowing for trajectory tracking and source sampling. The lecture also covers the use of bacterial bioreporters for specific chemical targets and the benchmarking of gill sensors with various samples. The Swiss Research Program Nano-Tera is highlighted as a key player in engineering multi-scale systems for health, security, energy, and the environment.