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This lecture covers the basics of electron microscopy, including the organization of practical work sessions, sample preparation, and the interpretation of images. It delves into the history of electron microscopy, the interaction of radiation with matter, and the various mechanisms involved. The lecture also explores the importance of wavelength, energy, and detectors in electron microscopy, as well as the types of interactions between electrons and matter. Students will learn about the limitations of optical microscopy, the significance of electron scattering, and the practical applications of electron microscopy in various fields.