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This lecture covers the R3 test, a method to assess clay reactivity in cement. It includes the benchmark test of calcined clay strength, the influence of clay grade on mechanical properties, and the monitoring of pozzolanic reactivity. The mix design, settings for isothermal calorimetry experiments, sample preparation, and the R3 protocol for heat of hydration and chemically bound water are discussed. The R3 test is a rapid way to quantify clay reactivity, with good correlation to compressive strength.