Electrochemical Biosensors: Front-End Circuits

This lecture covers the design and implementation of front-end circuits for electrochemical biosensors, focusing on a Current-to-Frequency Converter used in glucose biosensors. The lecture explains the functional blocks of the circuitry, the encoding of faradaic current, sizing the capacitor to meet design specifications, and modifications for measuring reduction currents. Additionally, it addresses the selective monitoring of metabolites using a three-electrodes configuration. Temperature compensation in glucometers and a PTAT circuit for temperature measurement are also discussed.