This lecture covers the evolution of x86 and ARM processors, from the first microprocessors to modern architectures like Intel Skylake and AMD Zen 3. It delves into the features, pipeline stages, instruction encoding, and memory addressing modes of various processor generations, including Intel Pentium, PentiumPro, Nehalem, and AMD Hammer. The lecture also discusses the challenges faced in adapting superscalar ideas to x86 CISC architectures, as well as the advancements in instruction encoding and microarchitecture design over the years.