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This lecture covers the immune responses to different types of microbes, including extracellular bacteria, intracellular bacteria, fungi, viruses, protozoa, and multicellular parasites. It discusses the survival strategies of microbes, the mechanisms of tissue injury caused by host responses, and the immune evasion tactics employed by pathogens. The presentation delves into the innate and adaptive immunity to extracellular and intracellular bacteria, emphasizing the role of complement activation, phagocytosis, and antibody responses. It also explores the injurious effects of both innate and adaptive immunity, as well as the immune evasion strategies employed by bacteria. Furthermore, the lecture addresses immunity to fungi, viruses, and parasites, highlighting the challenges posed by antigenic variation and the mechanisms of immune evasion by these pathogens.
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