Sequence Control

This lecture explores the concept of sequence control in polymers, focusing on the control of monomer sequence in DNA and protein biosynthesis, limitations of conventional polymerization reactions, and strategies to enhance control over monomer sequence in synthetic polymers. It delves into the perfect control of chain length and sequence in biological polymers like proteins, the process of protein biosynthesis, and the information transfer during protein biosynthesis. The lecture also discusses the heterogeneity in synthetic polymers, the distribution of monomer sequences in copolymerizations, and methods to improve control over sequence, such as solid phase peptide synthesis and addition polymers.