Translation: Genetic Code Overview

This lecture covers the basic concepts of translation, including transcription, the genetic code, and post-translational modifications. It explains the process step by step, from the types of mutations to the translation initiation complex formation. The instructor discusses the ribosome's role in protein synthesis, the wobble phenomenon, and the binding of aminoacyl-tRNA. Furthermore, it delves into the elongation and termination phases, highlighting the importance of chaperones in protein folding and the consequences of misfolding. The lecture concludes with insights into protein degradation mechanisms and the formation of protein aggregates in various pathophysiological conditions.