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This lecture delves into the historical and philosophical debate surrounding the origin of the universe, exploring the clash between scientific theories like the Big Bang and religious beliefs. It covers key figures such as Georges Lemaitre and Einstein, their views on cosmology, and the emergence of quantum physics. The discussion extends to the anthropic principle, which questions the role of observers in the universe's existence, and the implications of reconciling science with religious interpretations. The lecture also addresses misconceptions and pseudo-scientific applications of quantum mechanics in spirituality, highlighting the ongoing tension between scientific inquiry and religious dogma.