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This lecture covers the indirect detection of dark matter through astrophysical evidence, focusing on weakly interacting massive particles (WIMPs). It discusses the annihilation signal, gamma-ray sky observations, and the limit on the dark matter cross-section. The presentation explores the detection of dark matter in the Milky Way galaxy, including the radial profile of the dark matter halo and the gamma-ray glow. The lecture also delves into supermassive black holes and active galactic nuclei, emphasizing the annihilation spectra and the flux from dark matter halos. Practical exercises involve calculating the flux from dark matter halos and producing maps of gamma-ray emissions using Fermi LAT telescope data.