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This lecture explores the use of graphene and graphene-based materials for developing efficient bidirectional communication interfaces with the nervous system. It covers the challenges faced by current technologies in neural interfaces and discusses the potential of graphene in addressing these shortcomings. The presentation delves into various graphene-based technologies and devices for neural interfaces, aiming to establish reliable communication with the nervous system. Topics include multifunctional neural interfaces, high-performing passive electrodes, and the technology maturity of graphene-based devices. The lecture also touches upon the clinical translation of graphene technology by INBRAIN Neuroelectronics and the challenges and opportunities in the field.