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This lecture explores the complexity of the immune system, focusing on dendritic cells, natural killer cells, cytokines, and the role of DNA in immunostimulation. It delves into techniques like flow cytometry, ELISA, and transcript profiling to analyze immune networks. The concept of immunoengineering is introduced, emphasizing the application of engineering principles to manipulate the immune system for therapeutic purposes. The lecture also discusses microengraving as a strategy to capture quantitative information from live cells, showcasing its potential in immunology research.