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This lecture by the instructor covers the topographic organization in the brain, focusing on the spatially ordered cortical representations of sensory surfaces and muscles. It discusses the detection of these maps using hemodynamic neuroimaging, specifically in the olfactory, motor, visual, auditory, and somatosensory cortices. The lecture also delves into retinotopy, the mapping of visual space onto the cortical surface, and the measurement of retinotopy using fMRI and PET. Furthermore, it explores the design of hemodynamic experiments, the subtraction method, and the different types of experimental designs. The session concludes with a discussion on the general linear model, statistical analysis, and the application of basic statistical tests in neuroimaging research.