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This lecture covers the concept of membrane equilibrium potential, including the Nernst equation and the Goldman-Hodgkin-Katz formulation. It explains the quantitative derivation of the equilibrium membrane potential and introduces the equivalent circuit model of the plasma membrane. The lecture also discusses the circuit model in resting state, graded response of the membrane potential based on cable theory, and compartment models of the membrane, including single and multi-compartment models. Furthermore, it delves into the organization of the nervous system, detailing the peripheral and central nervous systems, sensory and efferent divisions, and the role of the enteric nervous system.